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FACT SHEET
LEPTO
HARDJO-BOVIS
·
Leptospirosis is an important disease entity that can cause
substantial productivity and profitability losses in the
o
The primary cause of bovine leptospirosis in the
o
A study conducted in six states with a cross section of
environmental and management conditions representative of the
o
Another study suggested 59 percent of
o
Infection of human leptospirosis can occur through exposure
to urine, placentas or aborted calves from infected cows and cause a flu-like
disease.5,6
§
A medical study in
§
Prevention of leptospiral infection in producers by cattle
herd vaccination has become a common practice in New Zealand.8
·
Disease caused by Lepto hardjo-bovis is generally subclinical
in cattle and difficult to diagnose, the most common clinical presentations
include:
o
Fetal infections, with resulting abortions
o
Stillbirths
o
Birth of weak calves
o
Reduced reproductive performance
·
Most commercial 5-way leptospirosis vaccines in the
o
Hardjo prajitno is found primarily in the United Kingdom.6,9,10
o
The use of hardjo prajitno antigen in
·
Use of a Lepto hardjo-bovis vaccine with label indications
for year-long prevention of urinary shedding and renal colonization and that
preventsreproductive tract colonization, is an effective management tool for
helping to improve reproductive performance in U.S. beef and dairy herds.
o Bovi-Shield GOLD® HB* provides superior protection against Lepto hardjo-bovis for at least 365 days, which is unmatched in the industry.
*The Bovi-Shield GOLD line and PregGuard® GOLD FP® 10 are recommended for vaccination of healthy cows and heifers approximately 1 month prior to breeding. These products can also be administered to pregnant cattle provided they were vaccinated, according to label directions, with any Bovi-Shield GOLD FP or PregGuard GOLD FP vaccine prior to breeding initially and within 12 months thereafter. Failure to follow label directions may result in abortions. The Bovi-Shield GOLD line may be administered to calves nursing pregnant cows, provided their dams were vaccinated within the last 12 months as described above. Consistent with good vaccination practices, heifers should receive at least 2 vaccine doses, with the second dose administered approximately 30 days pre-breeding.
1
Thiermann, AB. Bovine leptospirosis:
bacteriologic versus serologic diagnosis of cows at slaughter. Am J Vet Res 1983 44:2244-2245.
2
Miller DA, Wilson MA, Beran GW. Survey to estimate prevalence of Leptospira interrogans
infection in mature cattle in the
3
Wikse SE, Rogers GM, et al. Herd prevalence and risk factors of Leptospira
infection in beef cow/calf operations in the
4 Bolin
CA. Bovine leptospirosis prevalent in
5
Talpada MT, Garvey N, Sprowls R, et al. Prevalence of leptospiral infection in
6
Disease caused by Leptospira spp. In:
Radostits OM, Blood DC, Gay CC eds. Veterinary
Medicine. 8th ed.
7
Thornley CN, Baker MB, Weinstein P,
8
MacKintosh CG, Schollum LM, Blackmore DK, et al. Epidemiology of leptospirosis
in dairy farm workers in the Manawatu. Part II. A case-control study of high and
low risk farms.
9
Perino LJ, Rupp GP. Immunization of the beef cow and its influence on fetal and
nonfetal calf health. Veterinary Clinics
of
10
LeFebvre RB,
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